Synthesis and Anticonvulsant Activity of a New Series of 1,4-Dihydropyridine Derivatives

نویسندگان

  • R. Surendra Kumar
  • A. Idhayadhulla
  • A. Jamal Abdul Nasser
  • S. Kavimani
  • S. Indumathy
چکیده

A series of 1,4-dihydropyridine derivatives (1a-g) were prepared from three compounds condensation reaction of ethylacetoacetate, aromatic aldehyde and ammonium hydroxide. A new series of compounds (2a-g) were prepared from compounds (1a-g) via reaction with thiosemicarbazide using the condensation method. The synthesized compounds were confirmed by IR, 1H NMR, 13C NMR, mass spectral and elemental analyses. The synthesized compounds (1a-g) and (2a-g) were also screened for anticoagulant properties.

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عنوان ژورنال:

دوره 72  شماره 

صفحات  -

تاریخ انتشار 2010